Product Name: Human CSF2 / GM-CSF Antibody (Namilumab, Research Use)
Catalog Number: NBR-0617
Target Name: CSF2 / GM-CSF
Trade Name: Namilumab
Antibody Drug Description: Namilumab (AMG203), an immunoglobulin G1 monoclonal antibody that binds with high affinity to granulocyte-macrophage colony-stimulating factor (GM-CSF), was evaluated in a phase II randomized, double-blind, placebo-controlled study to investigate the efficacy and safety in patients with rheumatoid arthritis (RA) with an inadequate response to methotrexate (MTX-IR) or anti-tumour necrosis factor therapy (TNF-IR). Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CSF2
Synonyms: GMCSF; Sargramostim; GM-CSF
Target Description: CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Pulmonary Alveolar Proteinosis and Mucositis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and Gene expression (Transcription). Gene Ontology (GO) annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding.
Ensembl: ENSG00000164400
Uniprot: P04141