Product Name: Human TRP1 / TYRP1 Antibody (Flanvotumab, Research Use)
Catalog Number: NBR-0622
Target Name: TRP1 / TYRP1
Trade Name: Flanvotumab
Antibody Drug Description: Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TRP1
Synonyms: HTRP-1; Short Transient Receptor Potential Channel 1; TRPC1
Target Description: TRPC1 (Transient Receptor Potential Cation Channel Subfamily C Member 1) is a Protein Coding gene. Diseases associated with TRPC1 include Pyloric Stenosis and Immunodeficiency 10. Among its related pathways are Cardiac conduction and Nervous system development. Gene Ontology (GO) annotations related to this gene include monoatomic ion channel activity and calcium channel activity. An important paralog of this gene is TRPC4.
Ensembl: ENSG00000144935
Uniprot:  P48995