Product Name: Human CTLA-4 / CD152 Antibody (Zalifrelimab, Research Use)
Catalog Number: NBR-0625
Target Name: CTLA-4 / CD152
Trade Name: Zalifrelimab
Antibody Drug Description: Zalifrelimab is an antibody, a protein designed to interact with a specific target, that binds to and blocks CTLA4. This prevents CTL4 from binding to its targets, which reduces the CTLA-4-mediated inhibition of T-cells. It is hoped that through this mechanism, zalifrelimab will cause an increase in the number of activated T-cells in the tumor environment, allowing the immune system to effectively target and kill the cancer's cells. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: CD152
Synonyms: CD152; GSE; CD
Target Description: CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4) is a Protein Coding gene. Diseases associated with CTLA4 include Immune Dysregulation With Autoimmunity, Immunodeficiency, And Lymphoproliferation and Celiac Disease 3. Among its related pathways are Gene expression (Transcription) and CD28 co-stimulation. An important paralog of this gene is CD28.
Ensembl: ENSG00000163599
Uniprot: P16410