【Introduction】
Product Name: Human CTLA-8 / IL-17a Antibody (Ixekizumab, Research Use)
Catalog Number: NBR-0627
Target Name: CTLA-8 / IL-17a
Trade Name: Ixekizumab
Antibody Drug Description: Ixekizumab is an interleukin (IL)-17A antagonist that has been studied in three randomized, double-blind, placebo-controlled phase 3 trials (UNCOVER-1, UNCOVER-2, and UNCOVER-3).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CTLA-8
Synonyms: IL-17A; IL-17; CTLA8
Target Description: IL17A (Interleukin 17A) is a Protein Coding gene. Diseases associated with IL17A include Allergic Contact Dermatitis and Bronchiolitis Obliterans. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17F.
Ensembl: ENSG00000112115
Uniprot: Q16552