【Introduction】
Product Name: Human TGFb1 Antibody (Fresolimumab, Research Use)
Catalog Number: NBR-0642
Target Name: TGFb1
Trade Name: Fresolimumab
Antibody Drug Description: Fresolimumab (GC1008), a human IgG4κ monoclonal antibody that neutralizes TGFβ1, 2, and 3, demonstrated acceptable safety and antitumor activity in a phase 1 clinical trial for patients with malignant melanoma or renal carcinoma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TGFB1
Synonyms: CED; DPD1; TGFB; TGFbeta
Target Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
Ensembl: ENSG00000105329
Uniprot: TGFB1