【Introduction】
Product Name: Human EGFL7 Antibody (Parsatuzumab, Research Use)
Catalog Number: NBR-0647
Target Name: EGFL7
Trade Name: Parsatuzumab
Antibody Drug Description: Parsatuzumab (also known as MEGF0444A) is a humanized IgG1 monoclonal antibody that selectively blocks the interaction between EGFL7 and endothelial cells. In preclinical models, the addition of anti-EGFL7 enhanced the antiangiogenesis, tumor growth control, and survival associated with anti-VEGF monotherapy.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: EGFL7
Synonyms: ZNEU1
Target Description: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Ensembl: ENSG00000172889
Uniprot: Q9UHF1