【Introduction】
Product Name: Human ERBB1 / EGFR / HER1 Antibody (7A7, Research Use)
Catalog Number: NBR-0655
Target Name: ERBB1 / EGFR / HER1
Trade Name: 7A7
Antibody Drug Description: 7A7 is a recombinant fully human anti-EGFR monoclonal antibody. It is generated by immunization of Balb/c mice with the recombinant extracellular domain of murine EGFR (rECD-mEGFR). 7A7 recognized an epitope present in the amino acidic core of the antigen and is cross-reactive with the human EGFR.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533