【Introduction】
Product Name: Human ERBB1 / EGFR / HER1 Antibody (Duke D2C7, Research Use)
Catalog Number: NBR-0659
Target Name: ERBB1 / EGFR / HER1
Trade Name: Duke D2C7
Antibody Drug Description: D2C7-IT is a recombinant antibody fragment derived-IT with a high binding affinity for two of the most common established driver oncogenes of GBM, the wild type epidermal growth factor receptor (EGFRwt) and its mutant EGFR variant III (EGFRvIII). D2C7-IT has demonstrated a potent anti-tumor response in preclinical animal models of brain tumors.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533