【Introduction】
Product Name: Human TNFSF2 / TNFa Antibody (Golimumab, Research Use)
Catalog Number: NBR-0664
Target Name: TNFSF2 / TNFa
Trade Name: Golimumab
Antibody Drug Description: Golimumab (CNTO-148) is a potent human IgG1 TNFα antagonist monoclonal antibody. Golimumab has anti-inflammation activitity and inhibits IL-6 and IL-1β production. Golimumab acts via targeting and neutralizing TNF to prevent inflammation and destruction of cartilage and bone. Golimumab has the anticancer activity and induces cell apoptosis. Golimumab can be used for rheumatoid arthritis, Crohn's disease and cancer research.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: TNFSF2
Synonyms: TNF-Alpha; TNFSF2; TNFA; DIF
Target Description: TNF (Tumor Necrosis Factor) is a Protein Coding gene. Diseases associated with TNF include Malaria and Asthma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TNFR1 Pathway.
Ensembl: ENSG00000232810
Uniprot: P01375