【Introduction】
Product Name: Human EphA3 Antibody (Ifabotuzumab, Research Use)
Catalog Number: NBR-0670
Target Name: EphA3
Trade Name: Ifabotuzumab
Antibody Drug Description: Ifabotuzumab (formerly KB004) is a first-in-class therapeutic non-fucosylated IgG1 (human f-allotype) monoclonal antibody being developed by Humanigen (formerly KaloBios Pharmaceuticals) for the treatment of cancer. The drug was licensed from the Ludwig Institute for Cancer Research.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: EphA3
Synonyms: HEK4; TYRO4; ETK1
Target Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.
Ensembl: ENSG00000044524
Uniprot: P29320