
【Introduction】
Product Name: Human Sortilin / SORT1 Antibody (Latozinemab, Research Use)
Catalog Number: NBR-0696
Target Name: Sortilin / SORT1
Trade Name: Latozinemab
Antibody Drug Description: Latozinemab (formerly AL 001) is a microglia activating recombinant human anti-human sortilin (SORT1) monoclonal antibody, being developed by Alector.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: SORT1
Synonyms: Sortilin 1; Gp95; NT3
Target Description: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR).
Ensembl: ENSG00000134243
Uniprot: Q99523