Product Name: Human B7-H1 / PD-L1 / CD274 Antibody (Lodapolimab, Research Use)
Catalog Number: NBR-0699
Target Name: B7-H1 / PD-L1 / CD274
Trade Name: Lodapolimab
Antibody Drug Description: Lodapolimab is a fully human immunoglobulin G 1 lambda (IgG1λ) monoclonal antibody that binds to human PD-L1 expressed on tumour cells and tumor-infiltrating immune cells, prevents its binding to two receptors PD-1 and CD80 (B7-1), on the T cells. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  CD274
Synonyms: B7-H; B7-H1; B7H1; PD-L1; PDCD1LG1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7