Product Name: Human IGF1R / CD221 Antibody (LonigutamAb, Research Use)
Catalog Number: NBR-0702
Target Name: IGF1R / CD221
Trade Name: LonigutamAb
Antibody Drug Description: Lonigutamab (VB-421) is a subcutaneously delivered anti-IGF-1R that is currently being evaluated in a phase 1 study for thyroid eye disease. It is estimated to be a market opportunity worth over $4 billion.  Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IGF1R
Synonyms: CD221; IGFIR; IGFR; JTK13; MGC18216
Target Description: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.
Ensembl: ENSG00000140443
Uniprot: P08069