Product Name: Human ICOS / CD278 Antibody (MEDI-570, Research Use)
Catalog Number: NBR-0715
Target Name: ICOS / CD278
Trade Name: MEDI-570
Antibody Drug Description: MEDI-570 is an afucosylated human IgG1κ mAb, directed against the ligand binding domain of human ICOS. MEDI-570 displays relatively high (picomolar) binding to ICOS, which abrogates ICOS-mediated T cell proliferation and cytokine production. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ICOS
Synonyms: AILIM; CD278; CVID1
Target Description: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
Ensembl: ENSG00000163600
Uniprot: Q9Y6W8