
【Introduction】
Product Name: Human IgE (M1 prime) Antibody (Quilizumab, Research Use)
Catalog Number: NBR-0718
Target Name: IgE (M1 prime)
Trade Name: Quilizumab
Antibody Drug Description: Quilizumab is a humanized monoclonal antibody that targets the M1 prime segment of membrane-expressed IgE on IgE-switched B cells and plasmablasts. By causing the depletion of IgE-switched B cells and plasmablasts, it reduces serum IgE levels.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IGHE
Synonyms: N/A
Target Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.
Ensembl: ENSG00000211891
Uniprot: P01854