
【Introduction】
Product Name: Human IgE Antibody (Talizumab, Research Use)
Catalog Number: NBR-0721
Target Name: IgE
Trade Name: Talizumab
Antibody Drug Description: Talizumab is a humanized IgG1 mAb administered subcutaneously. Similar to omalizumab, it recognizes and masks an epitope in the CHε3 region of IgE responsible for binding to both FcεRI receptors on mast cells, basophils, and dendritic cells (DCs).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IGHE
Synonyms: N/A
Target Description: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.
Ensembl: ENSG00000211891
Uniprot: P01854