
【Introduction】
Product Name: Human FcRn (FCGRT & B2M) Antibody (Nipocalimab, Research Use)
Catalog Number: NBR-0730
Target Name: FcRn (FCGRT & B2M)
Trade Name: Nipocalimab
Antibody Drug Description: Nipocalimab (M281) is a fully human, recombinant, aglycosylated IgG1 monoclonal antibody. Nipocalimab is a human deglycosylated IgG1 anti-FcRn monoclonal antibody that binds with picomolar affinity to Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: FcRn
Synonyms: Fc Receptor
Target Description: Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk.
Ensembl: ENSG00000104870
Uniprot: P55899