【Introduction】
Product Name: Human IL-18 Antibody (ABT-325, Research Use)
Catalog Number: NBR-0742
Target Name: IL-18
Trade Name: ABT-325
Antibody Drug Description: ABT-325 (Human Anti-IL18 Recombinant Antibody) is an antibody which binds to human IL-18. The anti-IL-18 antibody can be used in clinical settings as well as in research and development.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-18
Synonyms: IL1F4; IGIF; IL-1g
Target Description: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators .
Ensembl: ENSG00000150782
Uniprot: Q14116