
【Introduction】
Product Name: Human IL-21 Antibody (Avizakimab, Research Use)
Catalog Number: NBR-0748
Target Name: IL-21
Trade Name: Avizakimab
Antibody Drug Description: Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21. Avizakimab (BOS161721) prevents IL-21 binding to the IL-21 receptor (IL-21R) and inhibits bioactivity.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-21
Synonyms: Za11; CVID11
Target Description: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers.
Ensembl: ENSG00000138684
Uniprot: Q9HBE4