Product Name: Human IL-23 Antibody (Mirikizumab, Research Use)
Catalog Number: NBR-0751
Target Name: IL-23
Trade Name: Mirikizumab
Antibody Drug Description: Mirikizumab (LY3074828) is a humanized antibody against the p19 subunit of IL-23 that is currently undergoing randomized, placebo-controlled trials to determine its efficacy for chronic plaque psoriasis. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-23
Synonyms: SGRF; IL-23a; P19;
Target Description: Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity. Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.
Ensembl: ENSG00000110944
Uniprot: Q9NPF7