Product Name: Human TIGIT Antibody (Ociperlimab, Research Use)
Catalog Number: NBR-0755
Target Name: TIGIT
Trade Name: Ociperlimab
Antibody Drug Description: Ociperlimab (BGB-A1217) is a humanized IgG1 monoclonal antibody developed by Beigene and developed worldwide. As an immune checkpoint candidate, ociperlimab is one of the most advanced anti-Tigit (T cell immunoglobulin and ITIM domain protein) antibodies currently in development with complete Fc function. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TIGIT
Synonyms: DKFZp667A205; FLJ39873; VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl: ENSG00000181847
Uniprot: Q495A1