
【Introduction】
Product Name: Human IL-4Ra / CD124 Antibody (MEDI2045, Research Use)
Catalog Number: NBR-0759
Target Name: IL-4Ra / CD124
Trade Name: MEDI2045
Antibody Drug Description: MEDI2045 is an IL-4Ra-neutralising antibody for the treatment of tevere uncontrolled asthma.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: IL-4Ra
Synonyms: CD124
Target Description: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.
Ensembl: ENSG00000077238
Uniprot: P24394