
【Introduction】
Product Name: Human Integrin aV / ITGAV / CD51 Antibody (Intetumumab, Research Use)
Catalog Number: NBR-0783
Target Name: Integrin aV / ITGAV / CD51
Trade Name: Intetumumab
Antibody Drug Description: Intetumumab is a fully human IgG1 monclonal antibody that targets to integrin alpha-V (ITGAV), which is encoded by the ITGAV gene. This drug was developed by Centocor Inc with the expectation for the treatment of solid tumors and has been investigated in trials studying the treatment of malignant melanoma and prostate cancer recently.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: ITGAV
Synonyms: CD51; MSK8; VNRA; VTNR
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF.
Ensembl: ENSG00000138448
Uniprot: P06756