
【Introduction】
Product Name: Human LAG3 / CD223 Antibody (Fianlimab, Research Use)
Catalog Number: NBR-0789
Target Name: LAG3 / CD223
Trade Name: Fianlimab
Antibody Drug Description: Fianlimab is a fully human monoclonal antibody targeting the immune checkpoint receptor LAG-3 on T cells and was invented using Regeneron's proprietary VelocImmune® technology. In melanoma, LAG-3 expression on cancer cells is associated with therapeutic resistance to PD-1 inhibitors.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: LAG3
Synonyms: CD223
Target Description: Lymphocyte activation gene 3 protein: Inhibitory receptor on antigen activated T-cells. Delivers inhibitory signals upon binding to ligands, such as FGL1 (By similarity).
Ensembl: ENSG00000089692
Uniprot: P18627