
【Introduction】
Product Name: Human B7-H1 / PD-L1 / CD274 Antibody (Opucolimab, Research Use)
Catalog Number: NBR-0792
Target Name: B7-H1 / PD-L1 / CD274
Trade Name: Opucolimab
Antibody Drug Description: Opucolimab is a monoclonal antibody against CD274 (PD-L1) that inhibits binding to the PDCD1 (PD1) receptor, potentially resulting in enhanced anti-tumor immune response.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CD274
Synonyms: B7-H; B7-H1; B7H1; PD-L1; PDCD1LG1; PDL1
Target Description: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.
Ensembl: ENSG00000120217
Uniprot: Q9NZQ7