
【Introduction】
Product Name: Human LIV-1 / SLC39A6 Antibody (LadiratuzumAb, Research Use)
Catalog Number: NBR-0793
Target Name: LIV-1 / SLC39A6
Trade Name: LadiratuzumAb
Antibody Drug Description: Ladiratuzumab vedotin (LV) is an investigational anti-LIV-1 antibody-drug conjugate with a protease-cleavable linker conjugated to monomethyl auristatin E (MMAE). LV 2.5 mg/kg given every 3 weeks (q3w) was generally well tolerated and has demonstrated encouraging efficacy in patients with pre-treated metastatic triple-negative breast cancer (mTNBC).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: SLC39A6
Synonyms: LIV-1
Target Description: May act as a zinc-influx transporter.
Ensembl: ENSG00000141424
Uniprot: Q13433