
【Introduction】
Product Name: Human CSF2 / GM-CSF Antibody (Otilimab, Research Use)
Catalog Number: NBR-0802
Target Name: CSF2 / GM-CSF
Trade Name: Otilimab
Antibody Drug Description: Otilimab (previously GSK3196165) is a fully human monoclonal antibody that inhibits granulocyte-macrophage colony-stimulating factor (GM-CSF), a protein that plays a central role in a broad range of immune-mediated diseases, including rheumatoid arthritis.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: CSF2
Synonyms: GMCSF; Sargramostim; GM-CSF
Target Description: CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Pulmonary Alveolar Proteinosis and Mucositis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and Gene expression (Transcription). Gene Ontology (GO) annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding.
Ensembl: ENSG00000164400
Uniprot: P04141