
【Introduction】
Product Name: Human NGF / bNGF Antibody (Fasinumab, Research Use)
Catalog Number: NBR-0808
Target Name: NGF / bNGF
Trade Name: Fasinumab
Antibody Drug Description: Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). It is currently under investigation for the treatment osteoarthritic pain 1 and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: NGF
Synonyms: NGFB
Target Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems 1, 2. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival 3 (Probable).
Ensembl: ENSG00000134259
Uniprot: P01138