
【Introduction】
Product Name: Human NGF / bNGF Antibody (MEDI-578, Research Use)
Catalog Number: NBR-0809
Target Name: NGF / bNGF
Trade Name: MEDI-578
Antibody Drug Description: MEDI-578 is a phage display derived anti-NGF antibody with a Kd of 69 pM. MEDI1912 was generated by in vitro affinity maturation of MEDI-578 and expressed transiently in a Chinese hamster ovary (CHO) cell line.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: NGF
Synonyms: NGFB
Target Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems 1, 2. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival 3 (Probable).
Ensembl: ENSG00000134259
Uniprot: P01138