
【Introduction】
Product Name: Human NGF / bNGF Antibody (PG110, Research Use)
Catalog Number: NBR-0810
Target Name: NGF / bNGF
Trade Name: PG110
Antibody Drug Description: PG110 (also known as ABT-110) is a humanized antibody developed by PanGenetics (an antibody development company, Utrecht, The Netherlands); it binds to NGF with high affinity and does not cross-react with other NTs and, therefore, is a highly specific function-blocking molecule that is able to neutralize NGF bioactivity .
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: NGF
Synonyms: NGFB
Target Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems 1, 2. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival 3 (Probable).
Ensembl: ENSG00000134259
Uniprot: P01138