
【Introduction】
Product Name: Human OSMR Antibody (Vixarelimab, Research Use)
Catalog Number: NBR-0813
Target Name: OSMR
Trade Name: Vixarelimab
Antibody Drug Description: Vixarelimab is an investigational fully-human monoclonal antibody that targets OSMRβ, which mediates signaling of interleukin-31 (IL-31) and oncostatin M (OSM), two key cytokines implicated in pruritus, inflammation and fibrosis.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: OSMR
Synonyms: N/A
Target Description: Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Ensembl: ENSG00000145623
Uniprot: Q99650