
【Introduction】
Product Name: Human Amyloid Beta Antibody (Ponezumab, Research Use)
Catalog Number: NBR-0816
Target Name: Amyloid Beta
Trade Name: Ponezumab
Antibody Drug Description: Ponezumab (PF-04360365) is a humanized anti–amyloid beta (Aβ) monoclonal antibody designed for treatment of Alzheimer disease (AD). It is an immunoglobulin G2 (IgG2) antibody targeted against an epitope encompassing the C‐terminal amino acids of the Aβ1-40 peptide derived from the human amyloid precursor protein (APP).
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: APP
Synonyms: AD1
Target Description: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis 1.
Ensembl: ENSG00000142192
Uniprot: P05067