
【Introduction】
Product Name: Human GDF15 / MIC-1 Antibody (Ponsegromab, Research Use)
Catalog Number: NBR-0818
Target Name: GDF15 / MIC-1
Trade Name: Ponsegromab
Antibody Drug Description: Ponsegromab (formerly PF-06946860) is subcutaneous, monoclonal antibody directed against the human growth differentiation factor 15 (GDF15; MIC-1). The drug is in Phase I clinical developmental studies for the treatment of Cachexia.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: GDF15
Synonyms: MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB
Target Description: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
Ensembl: ENSG00000130513
Uniprot: Q99988