Product Name: Human CTLA-4 / CD152 Antibody (Quavonlimab, Research Use)
Catalog Number: NBR-0824
Target Name: CTLA-4 / CD152
Trade Name: Quavonlimab
Antibody Drug Description: Quavonlimab (MK-1308) is a novel humanized immunoglobulin G1 monoclonal antibody that binds to CTLA-4 and blocks interaction with its ligands, CD80 and CD86. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name:  CTLA4
Synonyms: CD; CD152; CELIAC3; CTLA-4; GSE; IDDM12
Target Description: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Ensembl: ENSG00000163599
Uniprot:  P16410