
【Introduction】
Product Name: Human PDCD1 / PD-1 / CD279 Antibody (Penpulimab, Research Use)
Catalog Number: NBR-0839
Target Name: PDCD1 / PD-1 / CD279
Trade Name: Penpulimab
Antibody Drug Description: Penpulimab is a novel humanized IgG1 mAb that blocks PD-1 binding to PD-L1, engineered to eliminate FcγR binding and ADCC/ADCP completely.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PDCD1
Synonyms: CD279; hSLE1; PD-1; PD1; SLEB2
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116