Product Name: Human PDCD1 / PD-1 / CD279 Antibody (Zimberelimab, Research Use)
Catalog Number: NBR-0848
Target Name: PDCD1 / PD-1 / CD279
Trade Name: Zimberelimab
Antibody Drug Description: Zimberelimab is an anti-programmed cell death protein-1 (PD-1) monoclonal antibody being developed by Gloria Biosciences, Arcus Biosciences and Taiho Pharmaceutical Co. for the treatment of various cancers including cervical cancer, non-small cell lung cancer and classical Hodgkin's lymphoma. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: PDCD1
Synonyms: CD279; hSLE1; PD-1; PD1; SLEB2
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2. 
Ensembl: ENSG00000188389
Uniprot: Q15116