Product Name: Human TNFSF12 / TWEAK Antibody (RO5458640, Research Use)
Catalog Number: NBR-0850
Target Name: TNFSF12 / TWEAK
Trade Name: RO5458640
Antibody Drug Description: RO5458640 is a humanized monoclonal antibody against the TNF-like weak inducer of apoptosis (TWEAK) ligand, in Patients With Advanced Solid Tumors. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: TNFSF12
Synonyms: APO3L; DR3LG; TWEAK
Target Description: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Ensembl: ENSG00000239697
Uniprot: O43508