【Introduction】
Product Name: Human PDGFRB / CD140b Antibody (IMC-2C5, Research Use)
Catalog Number: NBR-0851
Target Name: PDGFRB / CD140b
Trade Name: IMC-2C5
Antibody Drug Description: Anti-PDGFRB ADCC Enhanced Antibody (IMC-2C5) is an ADCC enhanced antibody produced by Afuco™ platform. IMC-2C5 binds to both human and mouse PDGFRβ. And it is involved in the treatment of a broad range of human cancers.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: PDGFRB
Synonyms: CD140b; JTK12; PDGFR; PDGFR1
Target Description: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration.
Ensembl: ENSG00000113721
Uniprot: P09619