Product Name:

NebuSelect™ Recombinant Human IL-23R, mFc-tag

Catalog#:

NBL-240733

Description:

NebuSelect™ Recombinant Human IL-23R, mFc-tag(Cat#NBL-240733) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Gly24-Gly355.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 80-115 kDa based on Bis-Tris PAGE result.

Target Name:

IL-23R; IBD17; IL-23 R; IL-23 receptor

Target Information:

Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.

Amino Acid Sequence: 

Gly24-Gly355

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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